The protein encoded by this gene contains a leucine zipper-like motif and a proline-rich region that shares marked similarity with an SH3-binding domain. The protein localizes to the nucleus and is down-regulated in some cancer cell lines. It is thought to regulate the transcriptional response mediated by the nuclear factor kappa B (NF-kappaB). The gene has been proposed as a tumor suppressor gene whose protein product may have an important role in the development and/or progression of some cancers. [provided by RefSeq, Jul 2008]
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
LDOC1-20-RE | 20 (40 μL) | 200 μL | Request Pricing | |
LDOC1-20-OR | 20 (40 μL) | 200 μL | Request Pricing | |
LDOC1-20-GO | 20 (40 μL) | 200 μL | Request Pricing | |
LDOC1-20-GR | 20 (40 μL) | 200 μL | Request Pricing | |
LDOC1-20-AQ | 20 (40 μL) | 200 μL | Request Pricing |
The protein encoded by this gene contains a leucine zipper-like motif and a proline-rich region that shares marked similarity with an SH3-binding domain. The protein localizes to the nucleus and is down-regulated in some cancer cell lines. It is thought to regulate the transcriptional response mediated by the nuclear factor kappa B (NF-kappaB). The gene has been proposed as a tumor suppressor gene whose protein product may have an important role in the development and/or progression of some cancers. [provided by RefSeq, Jul 2008]
Gene Symbol : LDOC1
Gene Name : LDOC1, regulator of NFKB signaling
Chromosome : CHR X: 141,177,213-141,175,744
Locus : Xq27.1
Alt. Genes : LPCAT3
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