This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate the mature protein, which plays a role in left-right asymmetry determination of organ systems during development. This gene is closely linked to both a related family member and a related pseudogene. [provided by RefSeq, Aug 2016]
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
LEFTY1-20-RE | 20 (40 μL) | 200 μL | Request Pricing | |
LEFTY1-20-OR | 20 (40 μL) | 200 μL | Request Pricing | |
LEFTY1-20-GO | 20 (40 μL) | 200 μL | Request Pricing | |
LEFTY1-20-GR | 20 (40 μL) | 200 μL | Request Pricing | |
LEFTY1-20-AQ | 20 (40 μL) | 200 μL | Request Pricing |
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate the mature protein, which plays a role in left-right asymmetry determination of organ systems during development. This gene is closely linked to both a related family member and a related pseudogene. [provided by RefSeq, Aug 2016]
Gene Symbol : LEFTY1
Gene Name : Left-right determination factor 1
Chromosome : CHR 1: 225,889,145-225,886,281
Locus : 1q42.12
Alt. Genes : CCDC85B
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