This locus encodes a LEM domain-containing protein. The encoded protein functions to antagonize transforming growth factor-beta signaling at the inner nuclear membrane. Two transcript variants encoding different isoforms have been found for this gene. Mutations in this gene have been associated with osteopoikilosis, Buschke-Ollendorff syndrome and melorheostosis.[provided by RefSeq, Nov 2009]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| LEMD3-20-RE | 20 (40 μL) | 200 μL |  |
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| LEMD3-20-OR | 20 (40 μL) | 200 μL |  |
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| LEMD3-20-GO | 20 (40 μL) | 200 μL |  |
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| LEMD3-20-GR | 20 (40 μL) | 200 μL |  |
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| LEMD3-20-AQ | 20 (40 μL) | 200 μL |  |
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This locus encodes a LEM domain-containing protein. The encoded protein functions to antagonize transforming growth factor-beta signaling at the inner nuclear membrane. Two transcript variants encoding different isoforms have been found for this gene. Mutations in this gene have been associated with osteopoikilosis, Buschke-Ollendorff syndrome and melorheostosis.[provided by RefSeq, Nov 2009]
Gene Symbol : LEMD3
Gene Name : LEM domain containing 3
Chromosome : CHR 12: 651,695,70-652,483,60
Locus : 12q14.3
Alt. Genes : FEM1B
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