The protein encoded by this gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family. LIR family members are known to have activating and inibitory functions in leukocytes. Crosslink of this receptor protein on the surface of monocytes has been shown to induce calcium flux and secretion of several proinflammatory cytokines, which suggests the roles of this protein in triggering innate immune responses. This gene is one of the leukocyte receptor genes that form a gene cluster on the chromosomal region 19q13.4. Four alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| LILRA5-20-RE | 20 (40 μL) | 200 μL |  |
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| LILRA5-20-OR | 20 (40 μL) | 200 μL |  |
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| LILRA5-20-GO | 20 (40 μL) | 200 μL |  |
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| LILRA5-20-GR | 20 (40 μL) | 200 μL |  |
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| LILRA5-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family. LIR family members are known to have activating and inibitory functions in leukocytes. Crosslink of this receptor protein on the surface of monocytes has been shown to induce calcium flux and secretion of several proinflammatory cytokines, which suggests the roles of this protein in triggering innate immune responses. This gene is one of the leukocyte receptor genes that form a gene cluster on the chromosomal region 19q13.4. Four alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]
Gene Symbol : LILRA5
Gene Name : Leukocyte immunoglobulin like receptor A5
Chromosome : CHR 19: 543,131,38-543,070,69
Locus : 19q13.42
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