This gene produces an intronless transcript that is thought to function as a tumor suppressor. This transcript is downregulated in nasopharyngeal carcinoma and is a negative regulator of estrogen receptor signaling. A common polymorphism in this transcript allows the production of a 94 aa open reading frame in some individuals, which may interact directly with estrogen receptor 1 (PMID:15474036). This open reading frame does not exist on the reference genome haplotype, which is hypothesized to function through a non-coding RNA product. [provided by RefSeq, Mar 2017]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| LINC00312-20-RE | 20 (40 μL) | 200 μL |  |
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| LINC00312-20-OR | 20 (40 μL) | 200 μL |  |
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| LINC00312-20-GO | 20 (40 μL) | 200 μL |  |
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| LINC00312-20-GR | 20 (40 μL) | 200 μL |  |
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| LINC00312-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene produces an intronless transcript that is thought to function as a tumor suppressor. This transcript is downregulated in nasopharyngeal carcinoma and is a negative regulator of estrogen receptor signaling. A common polymorphism in this transcript allows the production of a 94 aa open reading frame in some individuals, which may interact directly with estrogen receptor 1 (PMID:15474036). This open reading frame does not exist on the reference genome haplotype, which is hypothesized to function through a non-coding RNA product. [provided by RefSeq, Mar 2017]
Gene Symbol : LINC00312
Gene Name : Long intergenic non-protein coding RNA 312
Chromosome : CHR 3: 857,178,1-857,466,7
Locus : 3p25.3
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