This gene encodes a B type nuclear lamin. The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Mutations in this gene are associated with acquired partial lipodystrophy. [provided by RefSeq, May 2012]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| LMNB2-20-RE | 20 (40 μL) | 200 μL |  |
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| LMNB2-20-OR | 20 (40 μL) | 200 μL |  |
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| LMNB2-20-GO | 20 (40 μL) | 200 μL |  |
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| LMNB2-20-GR | 20 (40 μL) | 200 μL |  |
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| LMNB2-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a B type nuclear lamin. The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Mutations in this gene are associated with acquired partial lipodystrophy. [provided by RefSeq, May 2012]
Gene Symbol : LMNB2
Gene Name : Lamin B2
Chromosome : CHR 19: 245,696,7-242,816,4
Locus : 19p13.3
Alt. Genes : HIPK3
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