LMO2 encodes a cysteine-rich, two LIM-domain protein that is required for yolk sac erythropoiesis. The LMO2 protein has a central and crucial role in hematopoietic development and is highly conserved. The LMO2 transcription start site is located approximately 25 kb downstream from the 11p13 T-cell translocation cluster (11p13 ttc), where a number T-cell acute lymphoblastic leukemia-specific translocations occur. Alternative splicing results in multiple transcript variants encoding different isoforms.[provided by RefSeq, Nov 2008]
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
LMO2-20-RE | 20 (40 μL) | 200 μL | Request Pricing | |
LMO2-20-OR | 20 (40 μL) | 200 μL | Request Pricing | |
LMO2-20-GO | 20 (40 μL) | 200 μL | Request Pricing | |
LMO2-20-GR | 20 (40 μL) | 200 μL | Request Pricing | |
LMO2-20-AQ | 20 (40 μL) | 200 μL | Request Pricing |
LMO2 encodes a cysteine-rich, two LIM-domain protein that is required for yolk sac erythropoiesis. The LMO2 protein has a central and crucial role in hematopoietic development and is highly conserved. The LMO2 transcription start site is located approximately 25 kb downstream from the 11p13 T-cell translocation cluster (11p13 ttc), where a number T-cell acute lymphoblastic leukemia-specific translocations occur. Alternative splicing results in multiple transcript variants encoding different isoforms.[provided by RefSeq, Nov 2008]
Gene Symbol : LMO2
Gene Name : LIM domain only 2
Chromosome : CHR 11: 338,922,88-338,585,75
Locus : 11p13
Alt. Genes : SGK2
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