This gene encodes a member of a subfamily of LIM domain proteins that are characterized by an N-terminal proline-rich region and three C-terminal LIM domains. The encoded protein localizes to the cell periphery in focal adhesions and may be involved in cell-cell adhesion and cell motility. This protein also shuttles through the nucleus and may function as a transcriptional co-activator. This gene is located at the junction of certain disease-related chromosomal translocations, which result in the expression of chimeric proteins that may promote tumor growth. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
LPP-20-RE | 20 (40 μL) | 200 μL | Request Pricing | |
LPP-20-OR | 20 (40 μL) | 200 μL | Request Pricing | |
LPP-20-GO | 20 (40 μL) | 200 μL | Request Pricing | |
LPP-20-GR | 20 (40 μL) | 200 μL | Request Pricing | |
LPP-20-AQ | 20 (40 μL) | 200 μL | Request Pricing |
This gene encodes a member of a subfamily of LIM domain proteins that are characterized by an N-terminal proline-rich region and three C-terminal LIM domains. The encoded protein localizes to the cell periphery in focal adhesions and may be involved in cell-cell adhesion and cell motility. This protein also shuttles through the nucleus and may function as a transcriptional co-activator. This gene is located at the junction of certain disease-related chromosomal translocations, which result in the expression of chimeric proteins that may promote tumor growth. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
Gene Symbol : LPP
Gene Name : LIM domain containing preferred translocation partner in lipoma
Chromosome : CHR 3: 188,153,049-188,890,670
Locus : 3q27.3-q28
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