This gene encodes a member of the LSm family of RNA-binding proteins. LSm proteins form stable heteromers that bind specifically to the 3'-terminal oligo(U) tract of U6 snRNA and may play a role in pre-mRNA splicing by mediating U4/U6 snRNP formation. Increased expression of this gene may play a role in cellular transformation and the progression of several malignancies including lung cancer, mesothelioma and breast cancer. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the short arm of chromosome 9. [provided by RefSeq, Nov 2011]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| LSM1-20-RE | 20 (40 μL) | 200 μL |  |
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| LSM1-20-OR | 20 (40 μL) | 200 μL |  |
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| LSM1-20-GO | 20 (40 μL) | 200 μL |  |
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| LSM1-20-GR | 20 (40 μL) | 200 μL |  |
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| LSM1-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the LSm family of RNA-binding proteins. LSm proteins form stable heteromers that bind specifically to the 3'-terminal oligo(U) tract of U6 snRNA and may play a role in pre-mRNA splicing by mediating U4/U6 snRNP formation. Increased expression of this gene may play a role in cellular transformation and the progression of several malignancies including lung cancer, mesothelioma and breast cancer. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the short arm of chromosome 9. [provided by RefSeq, Nov 2011]
Gene Symbol : LSM1
Gene Name : LSM1 homolog, mRNA degradation associated
Chromosome : CHR 8: 381,767,29-381,633,20
Locus : 8p11.23
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