The protein encoded by this gene is an enzyme that contains both hydrolase and aminopeptidase activities. The hydrolase activity is used in the final step of the biosynthesis of leukotriene B4, a proinflammatory mediator. The aminopeptidase activity has been shown to degrade proline-glycine-proline (PGP), a neutrophil chemoattractant and biomarker for chronic obstructive pulmonary disease (COPD). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2015]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| LTA4H-20-RE | 20 (40 μL) | 200 μL |  |
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| LTA4H-20-OR | 20 (40 μL) | 200 μL |  |
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| LTA4H-20-GO | 20 (40 μL) | 200 μL |  |
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| LTA4H-20-GR | 20 (40 μL) | 200 μL |  |
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| LTA4H-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene is an enzyme that contains both hydrolase and aminopeptidase activities. The hydrolase activity is used in the final step of the biosynthesis of leukotriene B4, a proinflammatory mediator. The aminopeptidase activity has been shown to degrade proline-glycine-proline (PGP), a neutrophil chemoattractant and biomarker for chronic obstructive pulmonary disease (COPD). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2015]
Gene Symbol : LTA4H
Gene Name : Leukotriene A4 hydrolase
Chromosome : CHR 12: 960,435,19-960,007,52
Locus : 12q23.1
Alt. Genes : LRPPRC
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