Inner mitochondrial membrane complex III (CIII) is the main enzyme complex in the mitochondrial respiratory chain, and Rieske Fe-S protein (UQCRFS1) is the last catalytic subunit added to the complex. The protein encoded by this gene is a nuclear-encoded mitochondrial matrix protein that stabilizes UQCRFS1 and chaperones it to the CIII complex. Defects in this gene are a cause of mitochondrial complex III deficiency, nuclear type 8. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jun 2014]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| LYRM7-20-RE | 20 (40 μL) | 200 μL |  |
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| LYRM7-20-OR | 20 (40 μL) | 200 μL |  |
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| LYRM7-20-GO | 20 (40 μL) | 200 μL |  |
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| LYRM7-20-GR | 20 (40 μL) | 200 μL |  |
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| LYRM7-20-AQ | 20 (40 μL) | 200 μL |  |
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Inner mitochondrial membrane complex III (CIII) is the main enzyme complex in the mitochondrial respiratory chain, and Rieske Fe-S protein (UQCRFS1) is the last catalytic subunit added to the complex. The protein encoded by this gene is a nuclear-encoded mitochondrial matrix protein that stabilizes UQCRFS1 and chaperones it to the CIII complex. Defects in this gene are a cause of mitochondrial complex III deficiency, nuclear type 8. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jun 2014]
Gene Symbol : LYRM7
Gene Name : LYR motif containing 7
Chromosome : CHR 5: 131,170,913-131,205,425
Locus : 5q23.3-q31.1
Alt. Genes : LRPPRC
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