MACC1 is a key regulator of the hepatocyte growth factor (HGF; MIM 142409)-HGF receptor (HGFR, or MET; MIM 164860) pathway, which is involved in cellular growth, epithelial-mesenchymal transition, angiogenesis, cell motility, invasiveness, and metastasis. Expression of MACC1 in colon cancer (MIM 114500) specimens is an independent prognostic indicator for metastasis formation and metastasis-free survival (Stein et al., 2009 [PubMed 19098908]).[supplied by OMIM, Mar 2009]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| MACC1-20-RE | 20 (40 μL) | 200 μL |  |
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| MACC1-20-OR | 20 (40 μL) | 200 μL |  |
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| MACC1-20-GO | 20 (40 μL) | 200 μL |  |
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| MACC1-20-GR | 20 (40 μL) | 200 μL |  |
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| MACC1-20-AQ | 20 (40 μL) | 200 μL |  |
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MACC1 is a key regulator of the hepatocyte growth factor (HGF; MIM 142409)-HGF receptor (HGFR, or MET; MIM 164860) pathway, which is involved in cellular growth, epithelial-mesenchymal transition, angiogenesis, cell motility, invasiveness, and metastasis. Expression of MACC1 in colon cancer (MIM 114500) specimens is an independent prognostic indicator for metastasis formation and metastasis-free survival (Stein et al., 2009 [PubMed 19098908]).[supplied by OMIM, Mar 2009]
Gene Symbol : MACC1
Gene Name : MACC1, MET transcriptional regulator
Chromosome : CHR 7: 202,173,89-201,346,54
Locus : 7p21.1
Alt. Genes : HIPK3
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