The protein encoded by this gene is an endothelial cell adhesion molecule that interacts preferentially with the leukocyte beta7 integrin LPAM-1 (alpha4beta7), L-selectin, and VLA-4 (alpha4beta1) on myeloid cells to direct leukocytes into mucosal and inflamed tissues. It is a member of the immunoglobulin family and is similar to ICAM1 and VCAM1. At least seven alternatively spliced transcripts encoding different protein isoforms have been found for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| MADCAM1-20-RE | 20 (40 μL) | 200 μL |  |
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| MADCAM1-20-OR | 20 (40 μL) | 200 μL |  |
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| MADCAM1-20-GO | 20 (40 μL) | 200 μL |  |
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| MADCAM1-20-GR | 20 (40 μL) | 200 μL |  |
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| MADCAM1-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene is an endothelial cell adhesion molecule that interacts preferentially with the leukocyte beta7 integrin LPAM-1 (alpha4beta7), L-selectin, and VLA-4 (alpha4beta1) on myeloid cells to direct leukocytes into mucosal and inflamed tissues. It is a member of the immunoglobulin family and is similar to ICAM1 and VCAM1. At least seven alternatively spliced transcripts encoding different protein isoforms have been found for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq, Jul 2008]
Gene Symbol : MADCAM1
Gene Name : Mucosal vascular addressin cell adhesion molecule 1
Chromosome : CHR 19: 496,489-505,342
Locus : 19p13.3
Alt. Genes : SERF2
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