The protein encoded by this gene is a basic leucine zipper (bZIP) transcription factor that lacks a transactivation domain. It is known to bind the US-2 DNA element in the promoter of the oxytocin receptor (OTR) gene and most likely heterodimerizes with other leucine zipper-containing proteins to enhance expression of the OTR gene during term pregnancy. The encoded protein can also form homodimers, and since it lacks a transactivation domain, the homodimer may act as a repressor of transcription. This gene may also be involved in the cellular stress response. Multiple transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jun 2009]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| MAFF-20-RE | 20 (40 μL) | 200 μL |  |
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| MAFF-20-OR | 20 (40 μL) | 200 μL |  |
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| MAFF-20-GO | 20 (40 μL) | 200 μL |  |
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| MAFF-20-GR | 20 (40 μL) | 200 μL |  |
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| MAFF-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene is a basic leucine zipper (bZIP) transcription factor that lacks a transactivation domain. It is known to bind the US-2 DNA element in the promoter of the oxytocin receptor (OTR) gene and most likely heterodimerizes with other leucine zipper-containing proteins to enhance expression of the OTR gene during term pregnancy. The encoded protein can also form homodimers, and since it lacks a transactivation domain, the homodimer may act as a repressor of transcription. This gene may also be involved in the cellular stress response. Multiple transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jun 2009]
Gene Symbol : MAFF
Gene Name : MAF bZIP transcription factor F
Chromosome : CHR 22: 382,019,31-382,165,10
Locus : 22q13.1
Alt. Genes : TRIM28
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