This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the downstream melanoma antigen family A, 5 (MAGEA5) gene.[provided by RefSeq, Oct 2011]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| MAGEA10-20-RE | 20 (40 μL) | 200 μL |  |
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| MAGEA10-20-OR | 20 (40 μL) | 200 μL |  |
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| MAGEA10-20-GO | 20 (40 μL) | 200 μL |  |
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| MAGEA10-20-GR | 20 (40 μL) | 200 μL |  |
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| MAGEA10-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the downstream melanoma antigen family A, 5 (MAGEA5) gene.[provided by RefSeq, Oct 2011]
Gene Symbol : MAGEA10
Gene Name : MAGE family member A10
Chromosome : CHR X: 152,138,577-152,133,309
Locus : Xq28
Alt. Genes : AGPAT1
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