This protein is the human homolog of mastermind, a Drosophila protein that plays a role in the Notch signaling pathway involved in cell-fate determination. There is in vitro evidence that the human homolog forms a complex with the intracellular portion of human Notch receptors and can increase expression of a Notch-induced gene. This evidence supports its proposed function as a transcriptional co-activator in the Notch signaling pathway. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| MAML1-20-RE | 20 (40 μL) | 200 μL |  |
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| MAML1-20-OR | 20 (40 μL) | 200 μL |  |
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| MAML1-20-GO | 20 (40 μL) | 200 μL |  |
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| MAML1-20-GR | 20 (40 μL) | 200 μL |  |
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| MAML1-20-AQ | 20 (40 μL) | 200 μL |  |
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This protein is the human homolog of mastermind, a Drosophila protein that plays a role in the Notch signaling pathway involved in cell-fate determination. There is in vitro evidence that the human homolog forms a complex with the intracellular portion of human Notch receptors and can increase expression of a Notch-induced gene. This evidence supports its proposed function as a transcriptional co-activator in the Notch signaling pathway. [provided by RefSeq, Jul 2008]
Gene Symbol : MAML1
Gene Name : Mastermind like transcriptional coactivator 1
Chromosome : CHR 5: 179,732,849-179,777,285
Locus : 5q35.3
Alt. Genes : FEM1B
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