The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically activates MAPK8/JNK1 and MAPK9/JNK2, and this kinase itself is phosphorylated and activated by MAP kinase kinase kinases including MAP3K1/MEKK1, MAP3K2/MEKK2,MAP3K3/MEKK5, and MAP4K2/GCK. This kinase is involved in the signal transduction mediating the cell responses to proinflammatory cytokines, and environmental stresses. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| MAP2K7-20-RE | 20 (40 μL) | 200 μL |  |
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| MAP2K7-20-OR | 20 (40 μL) | 200 μL |  |
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| MAP2K7-20-GO | 20 (40 μL) | 200 μL |  |
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| MAP2K7-20-GR | 20 (40 μL) | 200 μL |  |
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| MAP2K7-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically activates MAPK8/JNK1 and MAPK9/JNK2, and this kinase itself is phosphorylated and activated by MAP kinase kinase kinases including MAP3K1/MEKK1, MAP3K2/MEKK2,MAP3K3/MEKK5, and MAP4K2/GCK. This kinase is involved in the signal transduction mediating the cell responses to proinflammatory cytokines, and environmental stresses. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
Gene Symbol : MAP2K7
Gene Name : Mitogen-activated protein kinase kinase 7
Chromosome : CHR 19: 790,377,9-791,448,2
Locus : 19p13.2
Alt. Genes : YAF2
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