The protein encoded by this gene is a serine/threonine kinase and is part of some signal transduction cascades, including the ERK and JNK kinase pathways as well as the NF-kappa-B pathway. The encoded protein is activated by autophosphorylation and requires magnesium as a cofactor in phosphorylating other proteins. This protein has E3 ligase activity conferred by a plant homeodomain (PHD) in its N-terminus and phospho-kinase activity conferred by a kinase domain in its C-terminus. [provided by RefSeq, Mar 2012]
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
MAP3K1-20-RE | 20 (40 μL) | 200 μL | Request Pricing | |
MAP3K1-20-OR | 20 (40 μL) | 200 μL | Request Pricing | |
MAP3K1-20-GO | 20 (40 μL) | 200 μL | Request Pricing | |
MAP3K1-20-GR | 20 (40 μL) | 200 μL | Request Pricing | |
MAP3K1-20-AQ | 20 (40 μL) | 200 μL | Request Pricing |
The protein encoded by this gene is a serine/threonine kinase and is part of some signal transduction cascades, including the ERK and JNK kinase pathways as well as the NF-kappa-B pathway. The encoded protein is activated by autophosphorylation and requires magnesium as a cofactor in phosphorylating other proteins. This protein has E3 ligase activity conferred by a plant homeodomain (PHD) in its N-terminus and phospho-kinase activity conferred by a kinase domain in its C-terminus. [provided by RefSeq, Mar 2012]
Gene Symbol : MAP3K1
Gene Name : Mitogen-activated protein kinase kinase kinase 1
Chromosome : CHR 5: 568,150,72-568,961,51
Locus : 5q11.2
Alt. Genes : OPTN
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