The protein encoded by this gene is a member of the serine/threonine kinase family. This kinase contains a SH3 domain and a leucine zipper-basic motif. This kinase preferentially activates MAPK8/JNK kinase, and functions as a positive regulator of JNK signaling pathway. This kinase can directly phosphorylate, and activates IkappaB kinase alpha and beta, and is found to be involved in the transcription activity of NF-kappaB mediated by Rho family GTPases and CDC42. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| MAP3K11-20-RE | 20 (40 μL) | 200 μL |  |
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| MAP3K11-20-OR | 20 (40 μL) | 200 μL |  |
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| MAP3K11-20-GO | 20 (40 μL) | 200 μL |  |
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| MAP3K11-20-GR | 20 (40 μL) | 200 μL |  |
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| MAP3K11-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene is a member of the serine/threonine kinase family. This kinase contains a SH3 domain and a leucine zipper-basic motif. This kinase preferentially activates MAPK8/JNK kinase, and functions as a positive regulator of JNK signaling pathway. This kinase can directly phosphorylate, and activates IkappaB kinase alpha and beta, and is found to be involved in the transcription activity of NF-kappaB mediated by Rho family GTPases and CDC42. [provided by RefSeq, Jul 2008]
Gene Symbol : MAP3K11
Gene Name : Mitogen-activated protein kinase kinase kinase 11
Chromosome : CHR 11: 656,143,37-655,977,54
Locus : 11q13.1
Alt. Genes : CEBPZ
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