This gene encodes mitogen-activated protein kinase kinase kinase 14, which is a serine/threonine protein-kinase. This kinase binds to TRAF2 and stimulates NF-kappaB activity. It shares sequence similarity with several other MAPKK kinases. It participates in an NF-kappaB-inducing signalling cascade common to receptors of the tumour-necrosis/nerve-growth factor (TNF/NGF) family and to the interleukin-1 type-I receptor. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| MAP3K14-20-RE | 20 (40 μL) | 200 μL |  |
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| MAP3K14-20-OR | 20 (40 μL) | 200 μL |  |
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| MAP3K14-20-GO | 20 (40 μL) | 200 μL |  |
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| MAP3K14-20-GR | 20 (40 μL) | 200 μL |  |
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| MAP3K14-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes mitogen-activated protein kinase kinase kinase 14, which is a serine/threonine protein-kinase. This kinase binds to TRAF2 and stimulates NF-kappaB activity. It shares sequence similarity with several other MAPKK kinases. It participates in an NF-kappaB-inducing signalling cascade common to receptors of the tumour-necrosis/nerve-growth factor (TNF/NGF) family and to the interleukin-1 type-I receptor. [provided by RefSeq, Jul 2008]
Gene Symbol : MAP3K14
Gene Name : Mitogen-activated protein kinase kinase kinase 14
Chromosome : CHR 17: 453,170,63-452,631,18
Locus : 17q21.31
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