This gene is a member of the MAPKKK family of signal transduction molecules and encodes a protein with an N-terminal kinase catalytic domain, followed by a leucine zipper motif and a sterile-alpha motif (SAM). This magnesium-binding protein forms homodimers and is located in the cytoplasm. The protein mediates gamma radiation signaling leading to cell cycle arrest and activity of this protein plays a role in cell cycle checkpoint regulation in cells. The protein also has pro-apoptotic activity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| MAP3K20-20-RE | 20 (40 μL) | 200 μL |  |
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| MAP3K20-20-OR | 20 (40 μL) | 200 μL |  |
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| MAP3K20-20-GO | 20 (40 μL) | 200 μL |  |
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| MAP3K20-20-GR | 20 (40 μL) | 200 μL |  |
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| MAP3K20-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene is a member of the MAPKKK family of signal transduction molecules and encodes a protein with an N-terminal kinase catalytic domain, followed by a leucine zipper motif and a sterile-alpha motif (SAM). This magnesium-binding protein forms homodimers and is located in the cytoplasm. The protein mediates gamma radiation signaling leading to cell cycle arrest and activity of this protein plays a role in cell cycle checkpoint regulation in cells. The protein also has pro-apoptotic activity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
Gene Symbol : MAP3K20
Gene Name : Mitogen-activated protein kinase kinase kinase 20
Chromosome : CHR 2: 173,075,434-173,268,008
Locus : 2q31.1
Alt. Genes : FEM1B
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