This gene catalyzes a two-step reaction that involves the transfer of the adenosyl moiety of ATP to methionine to form S-adenosylmethionine and tripolyphosphate, which is subsequently cleaved to PPi and Pi. S-adenosylmethionine is the source of methyl groups for most biological methylations. The encoded protein is found as a homotetramer (MAT I) or a homodimer (MAT III) whereas a third form, MAT II (gamma), is encoded by the MAT2A gene. Mutations in this gene are associated with methionine adenosyltransferase deficiency. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| MAT1A-20-RE | 20 (40 μL) | 200 μL |  |
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| MAT1A-20-OR | 20 (40 μL) | 200 μL |  |
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| MAT1A-20-GO | 20 (40 μL) | 200 μL |  |
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| MAT1A-20-GR | 20 (40 μL) | 200 μL |  |
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| MAT1A-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene catalyzes a two-step reaction that involves the transfer of the adenosyl moiety of ATP to methionine to form S-adenosylmethionine and tripolyphosphate, which is subsequently cleaved to PPi and Pi. S-adenosylmethionine is the source of methyl groups for most biological methylations. The encoded protein is found as a homotetramer (MAT I) or a homodimer (MAT III) whereas a third form, MAT II (gamma), is encoded by the MAT2A gene. Mutations in this gene are associated with methionine adenosyltransferase deficiency. [provided by RefSeq, Jul 2008]
Gene Symbol : MAT1A
Gene Name : Methionine adenosyltransferase 1A
Chromosome : CHR 10: 802,900,02-802,718,19
Locus : 10q22.3
Alt. Genes : YAF2
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