MBTPS1 FISH Probe

This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an initial autocatalytic processing event in the ER to generate a heterodimer which exits the ER and sorts to the cis/medial-Golgi where a second autocatalytic event takes place and the catalytic activity is acquired. It encodes a type 1 membrane bound protease which is ubiquitously expressed and regulates cholesterol or lipid homeostasis via cleavage of substrates at non-basic residues. Mutations in this gene may be associated with lysosomal dysfunction. [provided by RefSeq, Feb 2014]


Gene Details
SKU Test Kits Buffer Dye Color Order Now
MBTPS1-20-RE 20 (40 μL) 200 μL color Request Pricing
MBTPS1-20-OR 20 (40 μL) 200 μL color Request Pricing
MBTPS1-20-GO 20 (40 μL) 200 μL color Request Pricing
MBTPS1-20-GR 20 (40 μL) 200 μL color Request Pricing
MBTPS1-20-AQ 20 (40 μL) 200 μL color Request Pricing

Gene Summary

This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an initial autocatalytic processing event in the ER to generate a heterodimer which exits the ER and sorts to the cis/medial-Golgi where a second autocatalytic event takes place and the catalytic activity is acquired. It encodes a type 1 membrane bound protease which is ubiquitously expressed and regulates cholesterol or lipid homeostasis via cleavage of substrates at non-basic residues. Mutations in this gene may be associated with lysosomal dysfunction. [provided by RefSeq, Feb 2014]

Gene Details

Gene Symbol : MBTPS1

Gene Name : Membrane bound transcription factor peptidase, site 1

Chromosome : CHR 16: 841,169,42-840,537,60

Locus : 16q23.3-q24.1

Alt. Genes : PREB

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