This gene product is a member of a family of proteins characterized by a specific cysteine-rich C-terminal domain, which is involved in transcriptional regulation of viral genome expression. Alternative translation initiation from an upstream non-AUG (GUG), and an in-frame, downstream AUG codon, results in the production of two isoforms, p40 and p32, respectively, which have different subcellular localization; p32 is mainly found in the cytoplasm, whereas p40 is targeted to the nucleolus. Both isoforms have transcriptional regulatory activity that is attributable to the cysteine-rich C-terminal domain. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| MDFIC-20-RE | 20 (40 μL) | 200 μL |  |
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| MDFIC-20-OR | 20 (40 μL) | 200 μL |  |
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| MDFIC-20-GO | 20 (40 μL) | 200 μL |  |
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| MDFIC-20-GR | 20 (40 μL) | 200 μL |  |
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| MDFIC-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene product is a member of a family of proteins characterized by a specific cysteine-rich C-terminal domain, which is involved in transcriptional regulation of viral genome expression. Alternative translation initiation from an upstream non-AUG (GUG), and an in-frame, downstream AUG codon, results in the production of two isoforms, p40 and p32, respectively, which have different subcellular localization; p32 is mainly found in the cytoplasm, whereas p40 is targeted to the nucleolus. Both isoforms have transcriptional regulatory activity that is attributable to the cysteine-rich C-terminal domain. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
Gene Symbol : MDFIC
Gene Name : MyoD family inhibitor domain containing
Chromosome : CHR 7: 114,922,153-115,019,915
Locus : 7q31.1-q31.2
Alt. Genes : LRPPRC
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