Malic enzyme catalyzes the oxidative decarboxylation of malate to pyruvate using either NAD+ or NADP+ as a cofactor. Mammalian tissues contain 3 distinct isoforms of malic enzyme: a cytosolic NADP(+)-dependent isoform, a mitochondrial NADP(+)-dependent isoform, and a mitochondrial NAD(+)-dependent isoform. This gene encodes a mitochondrial NADP(+)-dependent isoform. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ME3-20-RE | 20 (40 μL) | 200 μL |  |
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| ME3-20-OR | 20 (40 μL) | 200 μL |  |
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| ME3-20-GO | 20 (40 μL) | 200 μL |  |
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| ME3-20-GR | 20 (40 μL) | 200 μL |  |
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| ME3-20-AQ | 20 (40 μL) | 200 μL |  |
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Malic enzyme catalyzes the oxidative decarboxylation of malate to pyruvate using either NAD+ or NADP+ as a cofactor. Mammalian tissues contain 3 distinct isoforms of malic enzyme: a cytosolic NADP(+)-dependent isoform, a mitochondrial NADP(+)-dependent isoform, and a mitochondrial NAD(+)-dependent isoform. This gene encodes a mitochondrial NADP(+)-dependent isoform. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq, Jul 2008]
Gene Symbol : ME3
Gene Name : Malic enzyme 3
Chromosome : CHR 11: 866,747,44-864,411,07
Locus : 11q14.2
Alt. Genes : OPTN
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