The protein encoded by this gene is a transcriptional regulator and oncoprotein that may be involved in hematopoiesis, apoptosis, development, and cell differentiation and proliferation. The encoded protein can interact with CTBP1, SMAD3, CREBBP, KAT2B, MAPK8, and MAPK9. This gene can undergo translocation with the AML1 gene, resulting in overexpression of this gene and the onset of leukemia. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Mar 2011]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| MECOM-20-RE | 20 (40 μL) | 200 μL |  |
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| MECOM-20-OR | 20 (40 μL) | 200 μL |  |
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| MECOM-20-GO | 20 (40 μL) | 200 μL |  |
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| MECOM-20-GR | 20 (40 μL) | 200 μL |  |
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| MECOM-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene is a transcriptional regulator and oncoprotein that may be involved in hematopoiesis, apoptosis, development, and cell differentiation and proliferation. The encoded protein can interact with CTBP1, SMAD3, CREBBP, KAT2B, MAPK8, and MAPK9. This gene can undergo translocation with the AML1 gene, resulting in overexpression of this gene and the onset of leukemia. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Mar 2011]
Gene Symbol : MECOM
Gene Name : MDS1 and EVI1 complex locus
Chromosome : CHR 3: 169,663,780-169,083,498
Locus : 3q26.2
Alt. Genes : LRPPRC
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