This gene encodes a component of the mediator complex (also known as TRAP, SMCC, DRIP, or ARC), a transcriptional coactivator complex thought to be required for the expression of almost all genes. The mediator complex is recruited by transcriptional activators or nuclear receptors to induce gene expression, possibly by interacting with RNA polymerase II and promoting the formation of a transcriptional pre-initiation complex. The product of this gene is proposed to form a sub-complex with MED12, cyclin C, and CDK8 that can negatively regulate transactivation by mediator. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| MED13-20-RE | 20 (40 μL) | 200 μL |  |
Request Pricing |
| MED13-20-OR | 20 (40 μL) | 200 μL |  |
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| MED13-20-GO | 20 (40 μL) | 200 μL |  |
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| MED13-20-GR | 20 (40 μL) | 200 μL |  |
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| MED13-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a component of the mediator complex (also known as TRAP, SMCC, DRIP, or ARC), a transcriptional coactivator complex thought to be required for the expression of almost all genes. The mediator complex is recruited by transcriptional activators or nuclear receptors to induce gene expression, possibly by interacting with RNA polymerase II and promoting the formation of a transcriptional pre-initiation complex. The product of this gene is proposed to form a sub-complex with MED12, cyclin C, and CDK8 that can negatively regulate transactivation by mediator. [provided by RefSeq, Jul 2008]
Gene Symbol : MED13
Gene Name : Mediator complex subunit 13
Chromosome : CHR 17: 620,659,82-619,426,04
Locus : 17q23.2
Alt. Genes : HIPK3
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