This gene encodes menin, a putative tumor suppressor associated with a syndrome known as multiple endocrine neoplasia type 1. In vitro studies have shown menin is localized to the nucleus, possesses two functional nuclear localization signals, and inhibits transcriptional activation by JunD, however, the function of this protein is not known. Two messages have been detected on northern blots but the larger message has not been characterized. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| MEN1-20-RE | 20 (40 μL) | 200 μL |  |
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| MEN1-20-OR | 20 (40 μL) | 200 μL |  |
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| MEN1-20-GO | 20 (40 μL) | 200 μL |  |
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| MEN1-20-GR | 20 (40 μL) | 200 μL |  |
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| MEN1-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes menin, a putative tumor suppressor associated with a syndrome known as multiple endocrine neoplasia type 1. In vitro studies have shown menin is localized to the nucleus, possesses two functional nuclear localization signals, and inhibits transcriptional activation by JunD, however, the function of this protein is not known. Two messages have been detected on northern blots but the larger message has not been characterized. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2008]
Gene Symbol : MEN1
Gene Name : Menin 1
Chromosome : CHR 11: 648,112,93-648,035,13
Locus : 11q13.1
Alt. Genes : TRIM28
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