This gene encodes a preproprotein that is proteolytically processed to form multiple protein products. The major encoded protein product, lactadherin, is a membrane glycoprotein that promotes phagocytosis of apoptotic cells. This protein has also been implicated in wound healing, autoimmune disease, and cancer. Lactadherin can be further processed to form a smaller cleavage product, medin, which comprises the major protein component of aortic medial amyloid (AMA). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| MFGE8-20-RE | 20 (40 μL) | 200 μL |  |
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| MFGE8-20-OR | 20 (40 μL) | 200 μL |  |
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| MFGE8-20-GO | 20 (40 μL) | 200 μL |  |
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| MFGE8-20-GR | 20 (40 μL) | 200 μL |  |
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| MFGE8-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a preproprotein that is proteolytically processed to form multiple protein products. The major encoded protein product, lactadherin, is a membrane glycoprotein that promotes phagocytosis of apoptotic cells. This protein has also been implicated in wound healing, autoimmune disease, and cancer. Lactadherin can be further processed to form a smaller cleavage product, medin, which comprises the major protein component of aortic medial amyloid (AMA). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015]
Gene Symbol : MFGE8
Gene Name : Milk fat globule-EGF factor 8 protein
Chromosome : CHR 15: 889,134,68-888,986,82
Locus : 15q26.1
Alt. Genes : G3BP1
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