This gene encodes a heavily glycosylated protein which is a ligand for the NKG2D type II receptor. Binding of the ligand activates the cytolytic response of natural killer (NK) cells, CD8 alphabeta T cells, and gammadelta T cells which express the receptor. This protein is stress-induced and is similar to MHC class I molecules; however, it does not associate with beta-2-microglobulin or bind peptides. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
MICB-20-RE | 20 (40 μL) | 200 μL | Request Pricing | |
MICB-20-OR | 20 (40 μL) | 200 μL | Request Pricing | |
MICB-20-GO | 20 (40 μL) | 200 μL | Request Pricing | |
MICB-20-GR | 20 (40 μL) | 200 μL | Request Pricing | |
MICB-20-AQ | 20 (40 μL) | 200 μL | Request Pricing |
This gene encodes a heavily glycosylated protein which is a ligand for the NKG2D type II receptor. Binding of the ligand activates the cytolytic response of natural killer (NK) cells, CD8 alphabeta T cells, and gammadelta T cells which express the receptor. This protein is stress-induced and is similar to MHC class I molecules; however, it does not associate with beta-2-microglobulin or bind peptides. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
Gene Symbol : MICB
Gene Name : MHC class I polypeptide-related sequence B
Chromosome : CHR 6: 314,948,80-315,111,23
Locus : 6p21.33
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