microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of target mRNAs. This microRNA represents the most abundant miRNA in the corneal and lens epithelia of the eye and has been shown to interfere with target binding by another miRNA, miR-205. Through regulation of the VEGF and Akt signaling pathways, this microRNA may inhibit corneal angiogenesis. Mutations in the seed region of this microRNA cause familial keratoconus with cataract, also known as EDICT syndrome. [provided by RefSeq, Mar 2017]
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
MIR184-20-RE | 20 (40 μL) | 200 μL | Request Pricing | |
MIR184-20-OR | 20 (40 μL) | 200 μL | Request Pricing | |
MIR184-20-GO | 20 (40 μL) | 200 μL | Request Pricing | |
MIR184-20-GR | 20 (40 μL) | 200 μL | Request Pricing | |
MIR184-20-AQ | 20 (40 μL) | 200 μL | Request Pricing |
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of target mRNAs. This microRNA represents the most abundant miRNA in the corneal and lens epithelia of the eye and has been shown to interfere with target binding by another miRNA, miR-205. Through regulation of the VEGF and Akt signaling pathways, this microRNA may inhibit corneal angiogenesis. Mutations in the seed region of this microRNA cause familial keratoconus with cataract, also known as EDICT syndrome. [provided by RefSeq, Mar 2017]
Gene Symbol : MIR184
Gene Name : MicroRNA 184
Chromosome : CHR 15: 792,097,87-792,098,70
Locus : 15q25.1
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