Abscission, the separation of daughter cells at the end of cytokinesis, is effected by endosomal sorting complexes required for transport III (ESCRT-III). The protein encoded by this gene functions as a homodimer, with the N-termini binding to a subset of ESCRT-III subunits and the C-termini binding to membranes. The encoded protein regulates ESCRT-III activity and is required for proper cytokinesis. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2016]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| MITD1-20-RE | 20 (40 μL) | 200 μL |  |
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| MITD1-20-OR | 20 (40 μL) | 200 μL |  |
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| MITD1-20-GO | 20 (40 μL) | 200 μL |  |
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| MITD1-20-GR | 20 (40 μL) | 200 μL |  |
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| MITD1-20-AQ | 20 (40 μL) | 200 μL |  |
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Abscission, the separation of daughter cells at the end of cytokinesis, is effected by endosomal sorting complexes required for transport III (ESCRT-III). The protein encoded by this gene functions as a homodimer, with the N-termini binding to a subset of ESCRT-III subunits and the C-termini binding to membranes. The encoded protein regulates ESCRT-III activity and is required for proper cytokinesis. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2016]
Gene Symbol : MITD1
Gene Name : Microtubule interacting and trafficking domain containing 1
Chromosome : CHR 2: 991,810,72-991,614,26
Locus : 2q11.2
Alt. Genes : HIPK3
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