This gene encodes a basic helix-loop-helix leucine zipper transcription factor of the Myc/Max/Mad superfamily. This protein forms a heterodimeric complex and binds and activates, in a glucose-dependent manner, carbohydrate response element (ChoRE) motifs in the promoters of triglyceride synthesis genes. The gene is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at chromosome 7q11.23. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| MLXIPL-20-RE | 20 (40 μL) | 200 μL |  |
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| MLXIPL-20-OR | 20 (40 μL) | 200 μL |  |
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| MLXIPL-20-GO | 20 (40 μL) | 200 μL |  |
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| MLXIPL-20-GR | 20 (40 μL) | 200 μL |  |
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| MLXIPL-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a basic helix-loop-helix leucine zipper transcription factor of the Myc/Max/Mad superfamily. This protein forms a heterodimeric complex and binds and activates, in a glucose-dependent manner, carbohydrate response element (ChoRE) motifs in the promoters of triglyceride synthesis genes. The gene is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at chromosome 7q11.23. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
Gene Symbol : MLXIPL
Gene Name : MLX interacting protein like
Chromosome : CHR 7: 736,245,42-735,931,93
Locus : 7q11.23
Alt. Genes : FAM13A
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