Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature enzyme. This enzyme may degrade collagen type IV, fibronectin, fibrinogen, and beta-casein, and activate matrix metalloproteinase-9 by cleavage. The protein differs from most MMP family members in that it lacks a conserved C-terminal protein domain. The encoded protein may promote cell invasion in multiple human cancers. [provided by RefSeq, May 2016]
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
MMP26-20-RE | 20 (40 μL) | 200 μL | Request Pricing | |
MMP26-20-OR | 20 (40 μL) | 200 μL | Request Pricing | |
MMP26-20-GO | 20 (40 μL) | 200 μL | Request Pricing | |
MMP26-20-GR | 20 (40 μL) | 200 μL | Request Pricing | |
MMP26-20-AQ | 20 (40 μL) | 200 μL | Request Pricing |
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature enzyme. This enzyme may degrade collagen type IV, fibronectin, fibrinogen, and beta-casein, and activate matrix metalloproteinase-9 by cleavage. The protein differs from most MMP family members in that it lacks a conserved C-terminal protein domain. The encoded protein may promote cell invasion in multiple human cancers. [provided by RefSeq, May 2016]
Gene Symbol : MMP26
Gene Name : Matrix metallopeptidase 26
Chromosome : CHR 11: 498,819,3-499,242,8
Locus : 11p15.4
Alt. Genes : HMGB1P4
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