MMP9 FISH Probe

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades type IV and V collagens. Studies in rhesus monkeys suggest that the enzyme is involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow, and murine studies suggest a role in tumor-associated tissue remodeling. [provided by RefSeq, Jul 2008]


Gene Details
SKU Test Kits Buffer Dye Color Order Now
MMP9-20-RE 20 (40 μL) 200 μL color Request Pricing
MMP9-20-OR 20 (40 μL) 200 μL color Request Pricing
MMP9-20-GO 20 (40 μL) 200 μL color Request Pricing
MMP9-20-GR 20 (40 μL) 200 μL color Request Pricing
MMP9-20-AQ 20 (40 μL) 200 μL color Request Pricing

Gene Summary

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades type IV and V collagens. Studies in rhesus monkeys suggest that the enzyme is involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow, and murine studies suggest a role in tumor-associated tissue remodeling. [provided by RefSeq, Jul 2008]

Gene Details

Gene Symbol : MMP9

Gene Name : Matrix metallopeptidase 9

Chromosome : CHR 20: 460,089,07-460,165,60

Locus : 20q13.12

Alt. Genes : MKRN3-AS1

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