The Myc/Max/Mad network comprises a group of transcription factors that co-interact to regulate gene-specific transcriptional activation or repression. This gene encodes a protein member of the Myc/Max/Mad network. This protein has a basic-Helix-Loop-Helix-zipper domain (bHLHzip) with which it binds the canonical DNA sequence CANNTG, known as the E box, following heterodimerization with Max proteins. This protein is likely a transcriptional repressor and an antagonist of Myc-dependent transcriptional activation and cell growth. This protein represses transcription by binding to DNA binding proteins at its N-terminal Sin3-interaction domain. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| MNT-20-RE | 20 (40 μL) | 200 μL |  |
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| MNT-20-OR | 20 (40 μL) | 200 μL |  |
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| MNT-20-GO | 20 (40 μL) | 200 μL |  |
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| MNT-20-GR | 20 (40 μL) | 200 μL |  |
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| MNT-20-AQ | 20 (40 μL) | 200 μL |  |
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The Myc/Max/Mad network comprises a group of transcription factors that co-interact to regulate gene-specific transcriptional activation or repression. This gene encodes a protein member of the Myc/Max/Mad network. This protein has a basic-Helix-Loop-Helix-zipper domain (bHLHzip) with which it binds the canonical DNA sequence CANNTG, known as the E box, following heterodimerization with Max proteins. This protein is likely a transcriptional repressor and an antagonist of Myc-dependent transcriptional activation and cell growth. This protein represses transcription by binding to DNA binding proteins at its N-terminal Sin3-interaction domain. [provided by RefSeq, Jul 2008]
Gene Symbol : MNT
Gene Name : MAX network transcriptional repressor
Chromosome : CHR 17: 240,096,3-238,405,9
Locus : 17p13.3
Alt. Genes : ENAM
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