Molybdenum cofactor biosynthesis is a conserved pathway leading to the biological activation of molybdenum. The protein encoded by this gene is involved in this pathway. This gene was originally thought to produce a bicistronic mRNA with the potential to produce two proteins (MOCS1A and MOCS1B) from adjacent open reading frames. However, only the first open reading frame (MOCS1A) has been found to encode a protein from the putative bicistronic mRNA, whereas additional splice variants are likely to produce a fusion between the two open reading frames. This gene is defective in patients with molybdenum cofactor deficiency, type A. A related pseudogene has been identified on chromosome 16. [provided by RefSeq, Nov 2017]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| MOCS1-20-RE | 20 (40 μL) | 200 μL |  |
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| MOCS1-20-OR | 20 (40 μL) | 200 μL |  |
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| MOCS1-20-GO | 20 (40 μL) | 200 μL |  |
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| MOCS1-20-GR | 20 (40 μL) | 200 μL |  |
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| MOCS1-20-AQ | 20 (40 μL) | 200 μL |  |
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Molybdenum cofactor biosynthesis is a conserved pathway leading to the biological activation of molybdenum. The protein encoded by this gene is involved in this pathway. This gene was originally thought to produce a bicistronic mRNA with the potential to produce two proteins (MOCS1A and MOCS1B) from adjacent open reading frames. However, only the first open reading frame (MOCS1A) has been found to encode a protein from the putative bicistronic mRNA, whereas additional splice variants are likely to produce a fusion between the two open reading frames. This gene is defective in patients with molybdenum cofactor deficiency, type A. A related pseudogene has been identified on chromosome 16. [provided by RefSeq, Nov 2017]
Gene Symbol : MOCS1
Gene Name : Molybdenum cofactor synthesis 1
Chromosome : CHR 6: 399,345,50-399,042,57
Locus : 6p21.2
Alt. Genes : LRPPRC
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