This locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| MSH2-20-RE | 20 (40 μL) | 200 μL |  |
Request Pricing |
| MSH2-20-OR | 20 (40 μL) | 200 μL |  |
Request Pricing |
| MSH2-20-GO | 20 (40 μL) | 200 μL |  |
Request Pricing |
| MSH2-20-GR | 20 (40 μL) | 200 μL |  |
Request Pricing |
| MSH2-20-AQ | 20 (40 μL) | 200 μL |  |
Request Pricing |
This locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]
Gene Symbol : MSH2
Gene Name : MutS homolog 2
Chromosome : CHR 2: 474,030,66-476,345,00
Locus : 2p21-p16.3
Alt. Genes : FEM1B
Lorem Ipsum is simply dummy text of the printing and typesetting industry.
Lorem Ipsum is simply dummy text of the printing and typesetting industry.