This gene encodes a member of the muscle segment homeobox gene family. The encoded protein functions as a transcriptional repressor during embryogenesis through interactions with components of the core transcription complex and other homeoproteins. It may also have roles in limb-pattern formation, craniofacial development, particularly odontogenesis, and tumor growth inhibition. Mutations in this gene, which was once known as homeobox 7, have been associated with nonsyndromic cleft lip with or without cleft palate 5, Witkop syndrome, Wolf-Hirschom syndrome, and autosomoal dominant hypodontia. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| MSX1-20-RE | 20 (40 μL) | 200 μL |  |
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| MSX1-20-OR | 20 (40 μL) | 200 μL |  |
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| MSX1-20-GO | 20 (40 μL) | 200 μL |  |
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| MSX1-20-GR | 20 (40 μL) | 200 μL |  |
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| MSX1-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the muscle segment homeobox gene family. The encoded protein functions as a transcriptional repressor during embryogenesis through interactions with components of the core transcription complex and other homeoproteins. It may also have roles in limb-pattern formation, craniofacial development, particularly odontogenesis, and tumor growth inhibition. Mutations in this gene, which was once known as homeobox 7, have been associated with nonsyndromic cleft lip with or without cleft palate 5, Witkop syndrome, Wolf-Hirschom syndrome, and autosomoal dominant hypodontia. [provided by RefSeq, Jul 2008]
Gene Symbol : MSX1
Gene Name : Msh homeobox 1
Chromosome : CHR 4: 485,966,4-486,393,5
Locus : 4p16.2
Alt. Genes : ZNF263
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