This gene encodes a member of the muscle segment homeobox gene family. The encoded protein is a transcriptional repressor whose normal activity may establish a balance between survival and apoptosis of neural crest-derived cells required for proper craniofacial morphogenesis. The encoded protein may also have a role in promoting cell growth under certain conditions and may be an important target for the RAS signaling pathways. Mutations in this gene are associated with parietal foramina 1 and craniosynostosis type 2. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| MSX2-20-RE | 20 (40 μL) | 200 μL |  |
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| MSX2-20-OR | 20 (40 μL) | 200 μL |  |
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| MSX2-20-GO | 20 (40 μL) | 200 μL |  |
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| MSX2-20-GR | 20 (40 μL) | 200 μL |  |
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| MSX2-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the muscle segment homeobox gene family. The encoded protein is a transcriptional repressor whose normal activity may establish a balance between survival and apoptosis of neural crest-derived cells required for proper craniofacial morphogenesis. The encoded protein may also have a role in promoting cell growth under certain conditions and may be an important target for the RAS signaling pathways. Mutations in this gene are associated with parietal foramina 1 and craniosynostosis type 2. [provided by RefSeq, Jul 2008]
Gene Symbol : MSX2
Gene Name : Msh homeobox 2
Chromosome : CHR 5: 174,724,494-174,730,898
Locus : 5q35.2
Alt. Genes : CELA3A
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