This gene encodes a member of the mucin family of proteins, which are highly glycosylated macromolecular components of mucus secretions. This family member is the major gel-forming mucin in mucus. It is a major contributor to the lubricating and viscoelastic properties of whole saliva, normal lung mucus and cervical mucus. This gene has been found to be up-regulated in some human diseases, including sinus mucosa of chronic rhinosinusitis (CRS), CRS with nasal polyposis, chronic obstructive pulmonary disease (COPD) and H. pylori-associated gastric disease, and it may be involved in the pathogenesis of these diseases. [provided by RefSeq, Jul 2010]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| MUC5B-20-RE | 20 (40 μL) | 200 μL |  |
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| MUC5B-20-OR | 20 (40 μL) | 200 μL |  |
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| MUC5B-20-GO | 20 (40 μL) | 200 μL |  |
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| MUC5B-20-GR | 20 (40 μL) | 200 μL |  |
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| MUC5B-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the mucin family of proteins, which are highly glycosylated macromolecular components of mucus secretions. This family member is the major gel-forming mucin in mucus. It is a major contributor to the lubricating and viscoelastic properties of whole saliva, normal lung mucus and cervical mucus. This gene has been found to be up-regulated in some human diseases, including sinus mucosa of chronic rhinosinusitis (CRS), CRS with nasal polyposis, chronic obstructive pulmonary disease (COPD) and H. pylori-associated gastric disease, and it may be involved in the pathogenesis of these diseases. [provided by RefSeq, Jul 2010]
Gene Symbol : MUC5B
Gene Name : Mucin 5B, oligomeric mucus/gel-forming
Chromosome : CHR 11: 122,306,4-126,217,5
Locus : 11p15.5
Alt. Genes : BET1
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