This gene encodes the major component of the vault complex. Vaults are multi-subunit ribonucleoprotein structures that may be involved in nucleo-cytoplasmic transport. The encoded protein may play a role in multiple cellular processes by regulating the MAP kinase, JAK/STAT and phosphoinositide 3-kinase/Akt signaling pathways. The encoded protein also plays a role in multidrug resistance, and expression of this gene may be a prognostic marker for several types of cancer. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, May 2012]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| MVP-20-RE | 20 (40 μL) | 200 μL |  |
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| MVP-20-OR | 20 (40 μL) | 200 μL |  |
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| MVP-20-GO | 20 (40 μL) | 200 μL |  |
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| MVP-20-GR | 20 (40 μL) | 200 μL |  |
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| MVP-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes the major component of the vault complex. Vaults are multi-subunit ribonucleoprotein structures that may be involved in nucleo-cytoplasmic transport. The encoded protein may play a role in multiple cellular processes by regulating the MAP kinase, JAK/STAT and phosphoinositide 3-kinase/Akt signaling pathways. The encoded protein also plays a role in multidrug resistance, and expression of this gene may be a prognostic marker for several types of cancer. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, May 2012]
Gene Symbol : MVP
Gene Name : Major vault protein
Chromosome : CHR 16: 298,203,93-298,480,38
Locus : 16p11.2
Alt. Genes : ZNF263
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