The protein encoded by this gene has a nuclear and a cytoplasmic form and is a member of both the dynamin family and the family of large GTPases. The nuclear form is localized in a granular pattern in the heterochromatin region beneath the nuclear envelope. A nuclear localization signal (NLS) is present at the amino terminal end of the nuclear form but is lacking in the cytoplasmic form due to use of an alternate translation start codon. This protein is upregulated by interferon-alpha but does not contain the antiviral activity of a similar myxovirus resistance protein 1. [provided by RefSeq, Jul 2008]
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
MX2-20-RE | 20 (40 μL) | 200 μL | Request Pricing | |
MX2-20-OR | 20 (40 μL) | 200 μL | Request Pricing | |
MX2-20-GO | 20 (40 μL) | 200 μL | Request Pricing | |
MX2-20-GR | 20 (40 μL) | 200 μL | Request Pricing | |
MX2-20-AQ | 20 (40 μL) | 200 μL | Request Pricing |
The protein encoded by this gene has a nuclear and a cytoplasmic form and is a member of both the dynamin family and the family of large GTPases. The nuclear form is localized in a granular pattern in the heterochromatin region beneath the nuclear envelope. A nuclear localization signal (NLS) is present at the amino terminal end of the nuclear form but is lacking in the cytoplasmic form due to use of an alternate translation start codon. This protein is upregulated by interferon-alpha but does not contain the antiviral activity of a similar myxovirus resistance protein 1. [provided by RefSeq, Jul 2008]
Gene Symbol : MX2
Gene Name : MX dynamin like GTPase 2
Chromosome : CHR 21: 413,619,85-414,089,42
Locus : 21q22.3
Alt. Genes : KCNMB2
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