This gene encodes a member of the Myc superfamily of basic helix-loop-helix leucine zipper transcriptional regulators. The encoded protein forms a heterodimer with the cofactor MAX which binds specific E-box DNA motifs in the promoters of target genes and regulates their transcription. Disruption of the MAX-MXD3 complex is associated with uncontrolled cell proliferation and tumorigenesis. Transcript variants of this gene encoding different isoforms have been described.[provided by RefSeq, Dec 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| MXD3-20-RE | 20 (40 μL) | 200 μL |  |
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| MXD3-20-OR | 20 (40 μL) | 200 μL |  |
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| MXD3-20-GO | 20 (40 μL) | 200 μL |  |
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| MXD3-20-GR | 20 (40 μL) | 200 μL |  |
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| MXD3-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the Myc superfamily of basic helix-loop-helix leucine zipper transcriptional regulators. The encoded protein forms a heterodimer with the cofactor MAX which binds specific E-box DNA motifs in the promoters of target genes and regulates their transcription. Disruption of the MAX-MXD3 complex is associated with uncontrolled cell proliferation and tumorigenesis. Transcript variants of this gene encoding different isoforms have been described.[provided by RefSeq, Dec 2008]
Gene Symbol : MXD3
Gene Name : MAX dimerization protein 3
Chromosome : CHR 5: 177,312,290-177,305,499
Locus : 5q35.3
Alt. Genes : RBM12
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