This gene is a member of the MAD gene family . The MAD genes encode basic helix-loop-helix-leucine zipper proteins that heterodimerize with MAX protein, forming a transcriptional repression complex. The MAD proteins compete for MAX binding with MYC, which heterodimerizes with MAX forming a transcriptional activation complex. Studies in rodents suggest that the MAD genes are tumor suppressors and contribute to the regulation of cell growth in differentiating tissues. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| MXD4-20-RE | 20 (40 μL) | 200 μL |  |
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| MXD4-20-OR | 20 (40 μL) | 200 μL |  |
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| MXD4-20-GO | 20 (40 μL) | 200 μL |  |
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| MXD4-20-GR | 20 (40 μL) | 200 μL |  |
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| MXD4-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene is a member of the MAD gene family . The MAD genes encode basic helix-loop-helix-leucine zipper proteins that heterodimerize with MAX protein, forming a transcriptional repression complex. The MAD proteins compete for MAX binding with MYC, which heterodimerizes with MAX forming a transcriptional activation complex. Studies in rodents suggest that the MAD genes are tumor suppressors and contribute to the regulation of cell growth in differentiating tissues. [provided by RefSeq, Jul 2008]
Gene Symbol : MXD4
Gene Name : MAX dimerization protein 4
Chromosome : CHR 4: 226,214,2-224,743,1
Locus : 4p16.3
Alt. Genes : ZNF263
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