This gene is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain. This protein is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of this gene is associated with a variety of tumors, most notably neuroblastomas. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2014]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| MYCN-20-RE | 20 (40 μL) | 200 μL |  |
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| MYCN-20-OR | 20 (40 μL) | 200 μL |  |
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| MYCN-20-GO | 20 (40 μL) | 200 μL |  |
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| MYCN-20-GR | 20 (40 μL) | 200 μL |  |
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| MYCN-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain. This protein is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of this gene is associated with a variety of tumors, most notably neuroblastomas. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2014]
Gene Symbol : MYCN
Gene Name : MYCN proto-oncogene, bHLH transcription factor
Chromosome : CHR 2: 159,404,37-159,470,06
Locus : 2p24.3
Alt. Genes : ABI2
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