The myosin II molecule is a multi-subunit complex consisting of two heavy chains and four light chains. This gene encodes a heavy chain of myosin II, which is a member of the motor-domain superfamily. The heavy chain includes a globular motor domain, which catalyzes ATP hydrolysis and interacts with actin, and a tail domain in which heptad repeat sequences promote dimerization by interacting to form a rod-like alpha-helical coiled coil. This heavy chain subunit is a slow-twitch myosin. Alternatively spliced transcript variants have been found, but the full-length nature of these variants is not determined. [provided by RefSeq, Mar 2010]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| MYH7B-20-RE | 20 (40 μL) | 200 μL |  |
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| MYH7B-20-OR | 20 (40 μL) | 200 μL |  |
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| MYH7B-20-GO | 20 (40 μL) | 200 μL |  |
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| MYH7B-20-GR | 20 (40 μL) | 200 μL |  |
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| MYH7B-20-AQ | 20 (40 μL) | 200 μL |  |
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The myosin II molecule is a multi-subunit complex consisting of two heavy chains and four light chains. This gene encodes a heavy chain of myosin II, which is a member of the motor-domain superfamily. The heavy chain includes a globular motor domain, which catalyzes ATP hydrolysis and interacts with actin, and a tail domain in which heptad repeat sequences promote dimerization by interacting to form a rod-like alpha-helical coiled coil. This heavy chain subunit is a slow-twitch myosin. Alternatively spliced transcript variants have been found, but the full-length nature of these variants is not determined. [provided by RefSeq, Mar 2010]
Gene Symbol : MYH7B
Gene Name : Myosin heavy chain 7B
Chromosome : CHR 20: 349,558,34-350,024,36
Locus : 20q11.22
Alt. Genes : CLEC3A
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