This gene encodes a reverse-direction motor protein that moves toward the minus end of actin filaments and plays a role in intracellular vesicle and organelle transport. The protein consists of a motor domain containing an ATP- and an actin-binding site and a globular tail which interacts with other proteins. This protein maintains the structural integrity of inner ear hair cells and mutations in this gene cause non-syndromic autosomal dominant and recessive hearing loss. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2014]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| MYO6-20-RE | 20 (40 μL) | 200 μL |  |
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| MYO6-20-OR | 20 (40 μL) | 200 μL |  |
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| MYO6-20-GO | 20 (40 μL) | 200 μL |  |
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| MYO6-20-GR | 20 (40 μL) | 200 μL |  |
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| MYO6-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a reverse-direction motor protein that moves toward the minus end of actin filaments and plays a role in intracellular vesicle and organelle transport. The protein consists of a motor domain containing an ATP- and an actin-binding site and a globular tail which interacts with other proteins. This protein maintains the structural integrity of inner ear hair cells and mutations in this gene cause non-syndromic autosomal dominant and recessive hearing loss. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2014]
Gene Symbol : MYO6
Gene Name : Myosin VI
Chromosome : CHR 6: 757,491,75-759,195,36
Locus : 6q14.1
Alt. Genes : FEM1B
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