This gene encodes a member of the myosin family of actin-based molecular motor heavy chain proteins. The protein represents an unconventional myosin; it should not be confused with the conventional non-muscle myosin-9 (MYH9). The protein has four IQ motifs located in the neck domain that bind calmodulin, which serves as a light chain. The protein complex has a single-headed structure and exhibits processive movement on actin filaments toward the minus-end. The protein also has rho-GTPase activity. Polymorphisms in this gene are associated with celiac disease and ulcerative colitis susceptibility. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| MYO9B-20-RE | 20 (40 μL) | 200 μL |  |
Request Pricing |
| MYO9B-20-OR | 20 (40 μL) | 200 μL |  |
Request Pricing |
| MYO9B-20-GO | 20 (40 μL) | 200 μL |  |
Request Pricing |
| MYO9B-20-GR | 20 (40 μL) | 200 μL |  |
Request Pricing |
| MYO9B-20-AQ | 20 (40 μL) | 200 μL |  |
Request Pricing |
This gene encodes a member of the myosin family of actin-based molecular motor heavy chain proteins. The protein represents an unconventional myosin; it should not be confused with the conventional non-muscle myosin-9 (MYH9). The protein has four IQ motifs located in the neck domain that bind calmodulin, which serves as a light chain. The protein complex has a single-headed structure and exhibits processive movement on actin filaments toward the minus-end. The protein also has rho-GTPase activity. Polymorphisms in this gene are associated with celiac disease and ulcerative colitis susceptibility. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
Gene Symbol : MYO9B
Gene Name : Myosin IXB
Chromosome : CHR 19: 170,757,80-172,132,94
Locus : 19p13.11
Alt. Genes : YAF2
Lorem Ipsum is simply dummy text of the printing and typesetting industry.
Lorem Ipsum is simply dummy text of the printing and typesetting industry.