The protein encoded by this gene belongs to a family of sarcomeric proteins that bind to calcineurin, a phosphatase involved in calcium-dependent signal transduction in diverse cell types. These family members tether calcineurin to alpha-actinin at the z-line of the sarcomere of cardiac and skeletal muscle cells, and thus they are important for calcineurin signaling. Mutations in this gene cause cardiomyopathy familial hypertrophic type 16, a hereditary heart disorder. [provided by RefSeq, Aug 2011]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| MYOZ2-20-RE | 20 (40 μL) | 200 μL |  |
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| MYOZ2-20-OR | 20 (40 μL) | 200 μL |  |
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| MYOZ2-20-GO | 20 (40 μL) | 200 μL |  |
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| MYOZ2-20-GR | 20 (40 μL) | 200 μL |  |
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| MYOZ2-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene belongs to a family of sarcomeric proteins that bind to calcineurin, a phosphatase involved in calcium-dependent signal transduction in diverse cell types. These family members tether calcineurin to alpha-actinin at the z-line of the sarcomere of cardiac and skeletal muscle cells, and thus they are important for calcineurin signaling. Mutations in this gene cause cardiomyopathy familial hypertrophic type 16, a hereditary heart disorder. [provided by RefSeq, Aug 2011]
Gene Symbol : MYOZ2
Gene Name : Myozenin 2
Chromosome : CHR 4: 119,135,783-119,187,788
Locus : 4q26
Alt. Genes : TRAP1
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